Colorado Federal Criminal Defense
Facing federal criminal charges in Colorado is one of the most serious situations a person can face. Federal prosecutors have substantial resources, investigators who have been building your case for months or years, and mandatory sentencing guidelines that leave little room for error. At The Ambeau Law Firm, we defend people charged with federal crimes in the United States District Court for the District of Colorado. As a Colorado federal criminal defense attorney, Jarrett Ambeau brings something most defense attorneys cannot: a trial lawyer who is also a court-qualified expert in forensic DNA interpretation.
Jarrett Ambeau is licensed to practice in federal court in Colorado — in the District of Colorado — and is ready to take federal cases now. He has tried more than 60 felony jury trials to verdict. He holds a Master of Science in Forensic DNA and Serology from the University of Florida. He has been qualified as an expert witness in forensic DNA interpretation in court, has challenged DNA evidence at the federal level, and brings that same analytical rigor to every case he handles. When evidence is the battlefield, you want someone who actually understands it.
Our team is known for its:
- Licensure in the United States District Court for the District of Colorado
- Court-qualified expertise in forensic DNA interpretation — trial attorney and expert in one
- More than 60 felony jury trials to verdict, including complex DNA and forensic science cases
- Serious federal defense strategy built on preparation, investigation, and relentless advocacy
Types of Federal Cases We Handle in Colorado
Federal charges carry federal consequences — mandatory minimums, sentencing guidelines, and prosecutors with effectively unlimited resources. The cases The Ambeau Law Firm handles in the District of Colorado include:
Drug Trafficking and Distribution (21 U.S.C. § 841)
Federal drug charges routinely involve forensic evidence — lab analysis of controlled substances, DNA on packaging, and cell phone location data. We know how to challenge each layer of that evidence, including the reliability of the lab analysis itself. Mandatory minimums in federal drug cases can be severe. Early, strategic defense work matters.
Violent Crimes and Firearms Offenses
Federal violent crime and firearms cases frequently turn on physical evidence — DNA touch samples, low copy number (LCN) DNA analysis, ballistics, and crime scene reconstruction. Jarrett Ambeau has filed Daubert challenges to LCN DNA evidence in federal court and understands the science well enough to expose its limits to a jury.
Sex Offenses and SANE Evidence
Federal sex offense prosecutions are among the most evidence-intensive cases in the criminal justice system. We scrutinize the collection, handling, and interpretation of biological evidence — chain of custody, lab protocols, mixture interpretation, and probabilistic genotyping software — with the same rigor as the scientists who produced it.
White Collar, Fraud, and Federal Conspiracy
Federal conspiracy charges are broad by design. We build defense strategies that attack the government’s theory of the case from the beginning — working toward trial while evaluating every pretrial motion that could suppress evidence, narrow the charges, or force early disclosure.
Cases Involving DNA or Forensic Science Evidence
When forensic evidence is central to the government’s case, you need an attorney who can do more than hire an expert — you need one who is the expert. Jarrett Ambeau brings court-qualified forensic DNA expertise to the examination of every piece of scientific evidence the government puts forward.
DNA and Forensic Science Defense: A Genuine Advantage
Most criminal defense attorneys hire a DNA expert when they need one. Jarrett Ambeau is one. That distinction changes what is possible at every stage of your defense.
Jarrett Ambeau holds a Master of Science in Forensic DNA and Serology from the University of Florida, where his coursework covered forensic DNA analysis, forensic genetics, probabilistic genotyping, laboratory quality assurance and quality control, forensic immunology, and mammalian molecular biology. He has completed additional forensic training with the National Institute of Standards and Technology (NIST), the American Academy of Forensic Sciences (AAFS), the National Forensic College at Cardozo Law School (with the Innocence Project), and the International Symposium on Human Identification.
He serves as an observer on the AAFS ASB Standards Board DNA Consensus Body — the group that writes the national standards governing how forensic DNA evidence is produced and validated. He is a member of the American Association for Laboratory Accreditation. He has taught DNA evidence to criminal defense attorneys across the country at CLE seminars for over a decade, including presentations on probabilistic genotyping software such as TrueAllele and STRmix. He has been featured in the Netflix documentary I Just Killed My Dad, reflecting his work at the intersection of high-stakes criminal defense and complex forensic evidence.
In practice, this means:
- We can read and interpret the raw electropherogram data — the actual output of the DNA testing — not just the lab’s summary report.
- We can identify whether the lab followed its own validated protocols, and whether deviations from those protocols affected the result.
- We can evaluate probabilistic genotyping software outputs (TrueAllele, STRmix, and others) and challenge the statistical weight assigned to a DNA match.
- We can assess mixture interpretation — cases where multiple contributors are present — and expose the assumptions built into the government’s analysis.
- We can file and argue Daubert motions to exclude unreliable DNA evidence before it reaches the jury.
Why Choose The Ambeau Law Firm for Colorado Federal Defense?
If you are facing federal charges, the outcome of your case can affect every part of your future — your freedom, your reputation, your family, and your career. Federal court is not a place for on-the-job learning. You need a trial attorney who has been in the fire before, who understands forensic evidence at the scientific level, and who builds a defense from the ground up — not a defense built around hoping the government makes a mistake.
At The Ambeau Law Firm, we believe every case deserves a strategic defense built on preparation, investigation, and relentless advocacy. Federal prosecutors build cases to win convictions. Our job is to challenge the evidence, expose weaknesses, and fight for the best possible outcome for our clients. An experienced defense attorney can shape how a case is presented to a judge and jury. The right strategy, the right cross-examination, and the right command of the forensic facts can change the direction of a case — and, in many situations, change a person’s life.
Here are a few reasons clients facing federal charges in Colorado choose The Ambeau Law Firm:
- Jarrett Ambeau is licensed in the U.S. District Court for the District of Colorado and is actively taking federal cases now.
- More than 60 felony jury trials to verdict — including complex cases built on DNA, forensic science, and expert testimony.
- Court-qualified expert in forensic DNA interpretation — qualified to challenge the science, not just hire someone who can.
- Featured in the Netflix documentary I Just Killed My Dad for his work at the intersection of criminal defense and forensic science.
- Personalized defense strategy tailored to the unique facts of your case — never a one-size-fits-all approach.
Frequently Asked Questions
Federal Criminal Defense in Colorado
Facing a federal charge in Colorado is frightening, and the questions come fast. Below are straight answers to what people ask us most. Every case is different, so treat these as a starting point — not legal advice for your specific situation.
Are you licensed to practice in federal court in Colorado?
Yes. Jarrett Ambeau is licensed in the United States District Court for the District of Colorado and is actively taking federal cases now. If you are facing federal criminal charges in Colorado, he can represent you. We do not handle Colorado state court cases at this time.
What types of federal cases do you handle in Colorado?
We handle federal criminal defense cases in the District of Colorado, including drug trafficking and distribution, firearms offenses, violent crimes, sex offenses, white collar crimes, fraud, federal conspiracy, and cases involving DNA or other forensic science evidence. If you are unsure whether your case is federal or state, contact us and we can help you understand the difference.
What makes The Ambeau Law Firm different from other Colorado defense attorneys?
Jarrett Ambeau is both a trial attorney and a court-qualified expert in forensic DNA interpretation. That combination is genuinely rare. Most defense attorneys hire an expert when they need one. Jarrett Ambeau is the expert. He holds a Master of Science in Forensic DNA and Serology, has been qualified as an expert witness in court, and has filed Daubert challenges to DNA evidence in federal court. When forensic science is part of the government’s case against you, that expertise makes a real difference.
What is forensic DNA evidence, and why does it matter in federal cases?
DNA evidence can appear in federal cases involving violent crimes, sexual offenses, drug trafficking (DNA on packaging), firearms charges, and more. The government’s lab results are not automatically reliable — labs can make errors, fail to follow validated protocols, or misinterpret mixture results involving multiple contributors. An attorney who understands the science can challenge the evidence at its foundation, not just argue around it.
What is probabilistic genotyping, and why does it matter?
Probabilistic genotyping software (such as TrueAllele and STRmix) is used by crime labs to interpret complex DNA mixtures and assign statistical weight to a potential match. These systems are not infallible — they rely on assumptions, input parameters, and validation studies that can be challenged. Jarrett Ambeau has presented on probabilistic genotyping at CLE seminars for over a decade and knows where these systems can fail and how to expose those failures in court.
Can you challenge DNA evidence that has already been admitted?
Yes. Challenging DNA evidence is not limited to pretrial Daubert motions. Even after evidence has been admitted, we can challenge the interpretation, the weight the jury should assign to it, and the conclusions the government’s expert is drawing. Cross-examination of a government DNA expert — conducted by someone who actually understands the underlying science — can be one of the most powerful tools in a federal defense.
Should I take a plea deal in a federal case?
That depends entirely on the facts of your case, the strength of the government’s evidence, and your goals. Federal plea agreements can offer reduced sentences, but they also carry significant consequences that follow you permanently. We never advise a client to take a plea without first thoroughly investigating the case, challenging the evidence, and understanding every option available. The decision is yours — our job is to make sure you have the full picture before you make it.
How do I get started?
Call us at 225-330-7009 or use the contact form on our website to request a confidential consultation. Tell us about your case, and we will tell you honestly whether and how we can help. Federal charges move quickly — the sooner you have an attorney, the more options you have.
Have a question that isn’t answered here? Talk to us directly. Schedule a confidential consultation →
The information above is general and for educational purposes only. It is not legal advice and does not create an attorney–client relationship. Federal criminal law and procedure are complex, and outcomes depend on the specific facts of each case. For advice about your situation, consult a licensed attorney.

